Cancer Research

Wechter, W. J., Leipold, D. D., Murray, Jr., E. D., Quiggle, D., McCracken, J. D., Barrios, R. S., and Greenberg, N. M. "E-7869 (R-flurbiprofen) Inhibits Progression of Prostate Cancer in the TRAMP Mouse" (2000) Cancer Res. 60:2203-2208.

Wechter, W. J., Leipold, D. D., Quiggle D. D., McCracken, J. D., Murray, Jr., E. D. and Loughman, B. E. "R-Flurbiprofen, A Chemopreventive and Treatment of Cancer" (2000) Inflammopharmacology 8:189-206.

Wechter, W. J., Murray, Jr., E. D., Kantoci, D., Quiggle D. D., Leipold, D. D., Gibson, K. M. and McCracken, J. D. "Treatment and Survival Study in the C57BL/6J-APCMin/+ (Min) Mouse with R-Flurbiprofen" (2000) Life Sciences 66:745-753.

Loughman, B.E., Wechter, W. J., Quiggle D. D., Lilly, M., Ruckle, H.C., Gutierrez, I., McCracken, J. D., Murray, Jr., E. D., Benaksas, E.J., Leipold, D. D. and Gibson, K.M. "Phase I-IIa Escalating Dose Studies of E-7869 (R-Flurbiprofen) in Normal Subjects and Prostate Cancer Patients" (1999) NCI Workshop on Strategies for Developing New Clinical Trials for Prostate Cancer Chemoprevention.

Wechter, W. J., Leipold, D. D., Murray, Jr., E. D., Quiggle D. D., McCracken, J. D., Barrios, R.S. and Greenberg, N.M. "The Tramp Mouse Model of Prostate Cancer: Effectiveness of E-7869" (1999) NCI Workshop on Strategies for Developing New Clinical Trials for Prostate Cancer Chemoprevention.

Wechter, W. J., McCracken, J. D., Kantoci, D., Murray, Jr., E. D., Quiggle D. D., Leipold, D. D., Gibson, K. M., Mineyama, Y. and Liu, Y. "Mechanism of Enhancement of Intestinal Ulcerogenicity of S-Aryl Propionic Acids by their R-Enantiomers in the Rat" (1998) Dig. Dis. Sci., 43:1264-1274.

Wechter, W. J., Kantoci, D., Murray, Jr., E. D., Quiggle D. D., Leipold, D. D., Gibson, K. M. and McCracken, J. D. "R-Flurbiprofen Chemoprevention and Treatment of Intestinal Adenomas in the APCMin/+ Mouse Model: Implications for Prophylaxis and Treatment of Colon Cancer" (1997) Cancer Res. 57:4316-4324.

McCracken, J. D., Liu, Y., Chase, R. L., Kantoci, D., Murray, Jr., E. D., Quiggle, D. D., Mineyama, Y., and Wechter, W.J., "The Antiproliferative Effects of the Enantiomers of Flurbiprofen" (1996) J. Clin. Pharm. 36:540-545.

Helzlsouer, K.S., Huang, H., Alberg, A.J., et al. "Association between alpha-tocopherol, gamma-tocopherol, selenium, and subsequent prostate cancer" J Natl Cancer Inst, 92:2018-2023 (2000).

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